BCAA

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About BCAA

On the role of health supplements in fitness,We don care before, But when we useing a month we will be exciting because of the effect,Successful fitness need hard exercise but also scientific diet and important nutrition supplement.

In recent years, branched-chain amino acid supplements have come back into vogue in the bodybuilding and fitness community, and with good reason. Theres more research that supports the use of BCAAs than most other supplements on the market. While BCAA supplementation may be useful for gaining mass, I believe BCAAs are especially helpful for maintaining muscle mass while on a calorie-deficit diet. They e particularly useful for bodybuilding competitors who take their physiques to the lean extreme.

Its well established that branched-chain amino acids (particularly leucine) stimulate protein synthesis, and might do so to a greater extent than a normal protein on its own. BCAAs also increase synthesis of the cellular machinery responsible for carrying out the process of protein synthesis. Thus, BCAAs not only increase the rate of protein synthesis, but they also increase the cells capacity for protein synthesis! Yep, you read that right.

BCAAs also work in your favor by reducing the rate of protein breakdown. They do this (primarily) by decreasing the activity of the components of the protein breakdown pathway, and also by decreasing the expression of several complexes involved in protein breakdown. (In this case, they decrease the amount of mRNA produced from the gene that codes for these components.)

References on BCAA

[1]. Zhang S, Zeng X, Ren M, Mao X, Qiao S.Novel metabolic and physiological functions of branched chain amino acids: a review.J Anim Sci Biotechnol. 2017 Jan 23

[2]. Zhenyukh O, Civantos E, Ruiz-Ortega M, Sánchez MS, Vázquez C, Peiró C, Egido J, Mas S.High concentration of branched-chain amino acids promotes oxidative stress, inflammation and migration of human peripheral blood mononuclear cells via mTORC1 activation.Free Radic Biol Med. 2017 Mar

[3]. Hong CR, Lee GW, Paik HD, Chang PS, Choi SJ.Influence of lysolecithin and Tween 80 on the colloidal stability of branched chain amino acids in a nanosuspension system.Food Chem. 2017 Apr 15

[4]. Lysenko EA, Vepkhvadze TF, Lednev EM, Vinogradova OL, Popov DV.Branched-chain amino acids administration suppresses endurance exercise-related activation of ubiquitin proteasome signaling in trained human skeletal muscle.J Physiol Sci. 2016 Dec 3.

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